A small subset of mesenchymal genes (CDH2, DKK1, SERPINE2, MATN3, APLP1, CXCL1, FOXC2, BMP1) in Basal BRCA has been validated in this PRC2+-CGI pool with SERPINE2 and CXCL1 being the 2 most commonly overlapping genes found in 7 and 6 cancer types, respectively. The gene discussed is CDH2; the disease is cancer.