Upon reanalysis of 7,174 cells, we found that the user-classified PD-1 intermediate (PD-1int) effector population (characterized by low expression of inhibitory receptors but moderate expression of cytotoxic molecules) and PD-1 high (PD-1hi) exhausted (characterized by high inhibitory receptor and high cytotoxic molecules expression) tumor-infiltrating CD8+ T cells express significantly more Fgl2 than naive (characterized by high levels of Tcf7, Sell, and low CD44 expression) CD8+ T cells at the tumor (Fig. 1f). The gene discussed is PDCD1; the disease is neoplasm.