In an analysis of publicly available data comparing exhausted vs. naive P14 CD8+ T cells isolated day 45 after LCMV-clone 13 infection deposited by Im et al. 23, the Fgl2 gene was significantly increased in exhausted P14 vs. naive P14 (FC = 8.425, log10pvalue = 6.873) (Fig. 3b). This evidence concerns the gene CD8A and infection.