CD34 and myelodysplastic syndrome: Using scRNAseq data from CD34+ cells from patients with del(5q) MDS, we have been able to identify cells with del(5q) and non-del(5q), which enabled us to compare the transcriptional profile and GRNs of both populations within the same patient, thereby mitigating potential confounding factors associated with interindividual variability and microenvironmental influences, and thus made strides in the understanding of the molecular pathogenesis of del(5q) MDS.