ALKBH4 and gastric cancer: We first detected the differential expression of nine ALKBH family proteins in gastric cancer tissues and normal tissues based on TCGA, TARGET, and GTEx databases, and found that in gastric cancer tissues, only ALKBH1, ALKBH4, ALKBH8, and FTO were highly expressed in gastric cancer tissues, among which FTO and ALKBH4 were differentially expressed in gastric cancer tissues and normal tissues, FTO and ALKBH4 were most significantly expressed in gastric cancer tissues and normal tissues (Fig. S1A).