Serum CXCL10 levels were 64.5 ± 54.2 pg/mL for pSS, 73.1 ± 189.8 pg/mL for RA, and 18.6 ± 18.1 pg/mL for HCs, with a significant difference between pSS and HCs (p < 0.001). Here, CXCL10 is linked to peeling skin syndrome.