It has been reported that the deletion of SWI/SNF complex subunits can increase the resistance of thyroid cancer to the redifferentiation effect of MAPK inhibition.[21] We wanted to verify whether the regulatory effect of SETMAR on the expression of SWI/SNF complex subunits can affect the sensitivity of thyroid cancer cells to MAPK inhibitor‐based redifferentiation therapies. This evidence concerns the gene SMARCA1 and thyroid gland carcinoma.