Furthermore, upon treating various types of tumour cell lines with FOXO1 inhibitors, we observed not only the upregulation of VEGFC, PD‐L1 and CCL4 but also varying degrees of increase in MOMP‐related molecules (such as BAX, BAK1, CASP3, STING, IRF3 and RELB). The gene discussed is IRF3; the disease is neoplasm.