With a layer of adhesive polydopamine, the resulting Cr@PD can conjugate readily with a phthalocyanine‐based fluorescent dye to give Cr@PD‐Pc for tumor imaging.[13] It can also encapsulate alpelisib (Alp), a potent chemotherapeutic agent for the treatment of advanced breast cancer harboring the PIK3CA mutation,[14] to afford Cr@PD‐Alp that can induce an additional anticancer effect. Here, PIK3CA is linked to neoplasm.