These genes were classified into the p53 signaling pathway, proteoglycans in cancer, renal cell carcinoma,etc., through KEGG pathway analysis (Figure 5B) and were functionally enriched in cell division, the cell cycle, regulation of the cell cycle,etc., according to Gene Ontology (GO) functional analysis (Figure 5C). Here, TP53 is linked to hereditary clear cell renal cell carcinoma.