IL4 and chronic kidney disease: The results showed that 17 genera were enriched in the CPZ group, which were related to metabolism and inflammation—for example, Lachnospiraceae_FCS020_group was increased in patients with chronic kidney disease (68), Ruminococcus_1 was positively correlated with the expression levels of proinflammatory cytokines tumor necrosis factor α (TNF-α) and interleukin-1β (IL-1β) in the offspring brain of maternal sleep deprivation rats (69), whereas Candidatus_Stoquefichus was negatively correlated with both TNF-α and IL-4 concentration during postpartum uterine recovery in mice (70).