We conducted molecular experiments to validate our findings, and the results of Western blot analysis revealed notable disparities in the expression levels of FDX1, LIAS, DLAT, DLST, GCSH, PDHB and PDHA1 in gastric cancer cells between the CSRS‐Low (AGS) and CSRS‐High (HGC‐27) subtypes. The gene discussed is FDX1; the disease is gastric cancer.