This affects various intracellular proteins(histone) and matrix proteins (collagen, vimentin, enolase, fibronectin,and fibrinogen).5 Other factors contributingto RA susceptibility include increased body mass index (BMI), inflammatorydietary patterns, and dental problems.6−9 RA primarily impacts aged people between50 and 60 years old, with a global prevalence of around 0.5% amongadults. The gene discussed is FN1; the disease is rheumatoid arthritis.