NSAIDs alleviate pain and inflammationby blocking cyclooxygenase (COX-1 and COX-2) enzymes.35 By blocking their production, NSAIDs provide quick painrelief for RA patients.36 Glucocorticoids,like prednisone and cortisone, are steroid hormones with potent anti-inflammatoryand immunosuppressive properties.37 Theycan be used as a bridge therapy for RA patients to rapidly reducepain and stiffness during high disease activity.38,39 While DMARDs can be more effective in managing RA over the long-term,they may take weeks to months to show their full effect40 (Table 2). Here, PTGS2 is linked to rheumatoid arthritis.