Among these, AMPs,such as MSI-78, LL-37, and amphipathic-d, are appealing dueto their ability to interact with and neutralize LPS, offering hopein preventing sepsis.17,27 In the present study, we investigateda group of peptides inspired and designed from the TLR-derived peptidesand alanine-leucine sequences to assess their capacity to neutralizeLPS and evaluate their toxicity. This evidence concerns the gene ADSL and Sepsis.