Similarly, T cell cytotoxicity markers CTSW, GZMA, GZMB, FCGR3A, NKG7, GNLY, CTSC, KLRK1, and GZMH were found significantly upregulated in both KPN_ ACU and KPN_REC groups (Figure 3F), indicating a significant increase in T cell killing ability during acute infection stage that persists into the recovery stage. Here, CTSW is linked to infection.