Our findings indicate that AURKB expression is positively correlated with the TMB in a variety of cancers, including ACC, BLCA, BRCA, CHOL, COAD, KICH, KIRC, LGG, LUAD, LUSC, MESO, PAAD, SARC, PRAD, SKCM, STAD, UCS and UCEC. The gene discussed is AURKB; the disease is cancer.