IDI2 and diabetes mellitus: The DQA2, FGF5, IDI2 (for participants without diabetes), and MICB (for Europeans without diabetes) were positively associated with annualized eGFR slope change (represented decreased risk), while UMOD, HLA-E (without diabetes), NFATC1 (without diabetes), PFKFB2 (with diabetes), and YOD1 (with diabetes) were negatively associated with the slope change (represented increased risk), which were consistent with the principal findings.