ZEB1 and PDL1 within the xenograft tumor tissues were labeled by IF staining, as shown in Fig. S17E-F, IFIT1 overexpression (TANs) significantly promoted the expression of ZEB1 and PDL1 (P < 0.0001), and NAMPT and VEGF signaling levels were altered accordingly (P < 0.0001), further supporting the conclusions of our in vitro experiments. The gene discussed is ZEB1; the disease is neoplasm.