To investigate the role of Wnt5a in the pathology of asthma, we first interrogated the transcript levels of WNT5A (Wnt5a) in the human bronchial epithelial cells (HBECs) from patients with asthma and lung from mice with asthma by analyzing the GEO datasets of human (GSE18965 (Kicic et al. 2010), GSE206680 (Murphy et al. 2023),), and GEO data of mouse (GSE165969 (Jaiswal et al. 2022), and GSE71822 (Eyring et al. 2018). The gene discussed is WNT5A; the disease is asthma.