IL10 and Addictive alcohol use: One study also revealed that the regulatory effect of IL-10 on GABA release in the amygdala of mice with alcohol addiction was comprehensively weakened, and the level of GABA release in the amygdala of mice with alcohol addiction increased after the remission of alcohol addiction, suggesting that the key mechanism involved in the effect of alcohol addiction is the dysfunction of IL-10 on GABA regulation.