Colzani et al. demonstrated that inflammatory cytokines including interleukin (IL)-6, IL-1β, IL-10, tumour necrosis factor alpha (TNF-α), C-reactive protein (CRP), and neutrophil to lymphocyte ratio with a specific reduction of CD4+ and CD8+ cells were at least in part responsible for the cardiovascular damage seen in COVID-19 and characterise the downstream activated pathways in human cardiomyocytes (Colzani et al. 2024). This evidence concerns the gene CRP and COVID-19.