In the non-healing/recurrent group, the DM duration, FPG, TC, HbA1c, CRP, BUN, Scr, and serum VEGF are significantly higher than those in the healing group (p < 0.001, p = 0.035, p < 0.001, p = 0.017, p < 0.001, p = 0.009, p = 0.012, p = 0.026, respectively). The gene discussed is VEGFA; the disease is diabetes mellitus.