Univariate analysis revealed that the following factors were significantly associated with LRD/LT: ACA positivity, the presence of liver cirrhosis (LC), the presence of CREST syndrome, AST > 43 U/L, ALT > 46 U/L, ALP > 499 U/L, TB > 0.97 mg/dL, ALB ≤ 3.6 g/dL and platelet (PLT) count ≤ 12.8 × 104/μL. This evidence concerns the gene GPT and cirrhosis of liver.