CD4 and neoplasm: Furthermore, flow cytometry analysis of the tumor samples revealed that although the proportion of CD45+, CD45+/CD19+, CD45+/CD3+, and CD45+/CD3+/CD4+ cells did not significantly differ, the proportion of CD45+/CD3+/CD8+ cells decreased in the shCXCR7 group compared with that in the scramble-control group (Supplementary Fig. S5D: gating strategy; Fig. 4D and Supplementary Fig. S5E, F for the data).