When NEAT1 was silenced in OVCAR3 cells, GO enrichment analysis showed that the DEGs were participated in response to stimulus, catalytic activity and organelle part (Supplementary Fig. 5D), and KEGG analysis showed that DEGs were involved in the p53 pathway, PI3K/AKT pathway and pathways in cancer (Fig. 7D). The gene discussed is AKT1; the disease is cancer.