Furthermore, we observed that the independent DEGs of silenced NEAT1 were involved in many cancer pathways, the MAPK pathway, the mTOR pathway, the Wnt pathway and the PI3K/AKT pathway, while the independent DEGs of silenced NEAT1 were only enriched in gastric cancer, breast cancer and hepatocellular carcinoma (Fig. 7G, H). Here, AKT1 is linked to hepatocellular carcinoma.