Additionally, clonal analysis revealed that both cohorts showed shared similar TCR expansion patterns with regard to CD8+ FGFBP2+ effector T (Teff), ZNF683+ resident memory T (Trm), CXCL13+ exhausted T (Tex), and FGFBP2+ NK cells, suggesting that immunochemotherapy could also yield a comparable immune response in EGFR-mutant NSCLC (Figure 4D). Here, FGFBP2 is linked to non-small cell lung carcinoma.