Pathway analyses with the KEGG and REAC databases revealed a significant enrichment of the Fanconi anemia (FA) repair pathway, with notable genes such as BRIP1 (FANCJ), FANCI, FANCA, SLX4 (FANCP), UBE2T (FANCT), and C19orf40 (FAAP24) (Figure 1—figure supplement 1C). This evidence concerns the gene BRIP1 and Fanconi anemia.