After adjusting for age, sex, race, and education levels, marital, smoking status, alcohol drinker, hypoglycemic medications, antihypertensive medications, lipid-lowering medications, diabetes, stroke, ASCVD, CKD, BMI, ALT, AST, albumin, bilirubin total, alkaline phosphatase, fast total cholesterol, and HDL-C (Model 3), HCV infection remained unrelated to hypertension and SBP (OR: 1.34, 95% CI 0.96–1.87 and β: -0.92, 95% CI -2.7–0.86). The gene discussed is GPT; the disease is Hypertension.