NR3C2 and pulmonary fibrosis: In the present study, we first investigated the antifibrotic effect of MR using a mouse model of pulmonary fibrosis and found that, at the doses used in these experiments, the anti-fibrotic effects of MR were slightly inferior to those of pirfenidone, which indicates that MR has high scientific research value, and remains a promising clinical prospect for treating lung fibrosis due to its unique advantages, including its abundant natural sources.