TGFB1 and pulmonary fibrosis: The expression of collagen-I, collagen-III, vimentin, α-SMA, snail was significantly increased after 72 h of TGF-β1 stimulation, and this elevated expression was dose-dependently reversed by exposure to MR (Figures 2B,C), indicating that MR could reduce the deposition of ECM, thereby attenuating the development of pulmonary fibrosis.