The expression of collagen-I, collagen-III, vimentin, α-SMA, snail was significantly increased after 72 h of TGF-β1 stimulation, and this elevated expression was dose-dependently reversed by exposure to MR (Figures 2B,C), indicating that MR could reduce the deposition of ECM, thereby attenuating the development of pulmonary fibrosis. Here, ACTA1 is linked to pulmonary fibrosis.