For example, MYCNOS, which is upregulated in hepatocellular carcinoma cells and tissues, affects disease progression, shortens patient survival (Yu et al., 2020) and acts as an endogenous sponge of miR-216b, thereby regulating the expression of FOXM1 and promoting the proliferation of glioblastoma cells (Zhao et al., 2021). This evidence concerns the gene FOXM1 and hepatocellular carcinoma.