Age of initial diagnosis, laboratory parameters gamma-glutamyltransferase (gamma-GT), alanine-transaminase (ALT), AP, bilirubin, model of endstage liver disease (MELD) score (≥5, ≥10, ≥15), Child-Pugh stage of liver cirrhosis (none, CHILD A, CHILD B, CHILD C), histological proof of diagnosis, dominant stenosis, performed liver transplantation, cholestasis, portal hypertension/hepatosplenomegaly, and autoimmune hepatitis (AIH)-PSC overlap syndrome were evaluated to phenotype the PSC patients (Table 2). The gene discussed is GPT; the disease is cirrhosis of liver.