A greater number of genes are upregulated in DCs after MRV infection, many of which are involved in the innate immune response (i.e. Ifit1, Ifit3, Mx1, Gbp2, Oasl1, Isg15, Ccr1, Ifitm2, Oaxl2, Casp1, Casp4) that would be predicted in response to a viral infection (Figure 7A). The gene discussed is IFIT1; the disease is viral infectious disease.