GSTK1 and GSTO1 are glutathione transferases that play an important role in inflammatory processes such as obesity, insulin resistance, and lipid peroxidation induced by high‐fat diets (Liu et al., 2012; Menon et al., 2017; Mosialou et al., 1993). The gene discussed is HPGDS; the disease is obesity due to melanocortin 4 receptor deficiency.