The CDKN2A was significantly upregulated in five tumors as shown in Figures 2A-2E among the four pathological stages of cancers as shown in Figures 2F-2J, including BRCA (num(T)=1085; num(N)=291), KICH (num(T)=66; num(N)=53), KIRC (num(T)=523; num(N)=100), and KIRP (num(T)=286; num(N)=60), and extremely significant in COAD (num(T)=275; num(N)=349). This evidence concerns the gene CDKN2A and cancer.