Though studies about Nfatc2ip in cardiac hypertrophy are scarce, Nfatc2ip is significantly upregulated in the third month after ST‐elevation myocardial infarction,11 some of which have proposed that Nfatc2ip is involved in common variable immunodeficiency28 or calcium channel TRPV6‐mediated breast cancer.29 This evidence concerns the gene TRPV6 and cardiac hypertrophy.