Several DNA repair pathways have been implicated in the cellular response to FA-induced genotoxic stress (7,8), including the interstrand-crosslinking (ICL) Fanconi anemia DNA repair pathway; the CSB protein, which initiates transcription-coupled repair (TCR) when RNA polymerase II stalls at a transcription blocking lesion; and the exonuclease 1 (EXO1) (9,10). This evidence concerns the gene EXO1 and Fanconi anemia.