Endoplasm reticulum‐associated pathways, encompassing ‘Response to endoplasmic reticulum stress’, ‘Endoplasmic reticulum unfolded protein response’ and ‘Intrinsic apoptotic signalling pathway in response to endoplasmic reticulum stress’, exhibited a predominant focus within C5 MUC2+ tumour cells. The gene discussed is MUC2; the disease is neoplasm.