ACTA1 and Myocardial fibrosis: Moreover, our results revealed that berberine dose‐dependently reduced myocardial fibrosis, which was supported by a decrease in fibrosis area (Figure 2H,I) and reduced expression of fibrosis‐related markers (COL1A1, COL3A1, TGF‐β and α‐SMA, Figure 2L,N–Q).