How these models translate to the human experience of pain is difficult to judge, but four effective migraine drugs that inhibit the effect of migraine‐provoking molecules have been identified: non‐steroidal anti‐inflammatory drugs (NSAIDs) which inhibit prostanoids, N(G)‐monomethyl l‐arginine which inhibits NO production [22], CGRP‐antagonizing drugs and PACAP‐inhibiting antibodies [9, 23]. Here, ADCYAP1 is linked to migraine disorder.