As previously noted in this review, various interleukins participate in the pathogenesis of RA, such as TNF-α, IL-1β, and IL-6, among others [28], as RA is a disease in which many of its comorbidities are associated with metabolic problems or muscle wasting, which contribute to functional disability and a worse disease prognosis [33,34,35]. The gene discussed is IL1B; the disease is rheumatoid arthritis.