SOD1 and Alzheimer disease: Oxidative damage along with accompanying enhanced lipid peroxidation and decreased activity of the major antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), as well as decreased levels of glutathione (GSH), have been shown to be characteristic features of AD and PD as well [215,216,217].