Watrowski et al. demonstrated a significant association between single-nucleotide polymorphisms’ (SNPs) genetic variation of interleukin-8 (IL-8), a pro-inflammatory and pro-angiogenic chemokine often altered in endometriosis and cancers and implicated in the activation of the PI3K/Akt pathway, and EAOC [157]. This evidence concerns the gene PIK3CA and cancer.