CD163 and neoplasm: For the clinico-pathologic association, the sCD163-tumor distance showed negative associations with grade, sCD163, tCD163, and tCD206 densities (p ≤ 0.048), while the sCD206-tumor distance was associated negatively with ER, PR, and tCD206 densities (p ≤ 0.045) (Table 2, Supplementary Figure S4).