KLK3 and neoplasm: In this study, we aimed to evaluate the influence of unfavorable tumor grade (ISUP grade group > 2) on PCa progression after RARP in a very favorable PCa population with low/intermediate risk-class features, presenting with PSA < 10 ng/mL, BPC < 50%, clinical stage cT1c (non-palpable tumors) and including biopsy ISUP grade groups 1 and 2.