IDH2 and diffuse large B-cell lymphoma: Further analysis of our DLBCL RNA-seq data showed that of the Hallmark oxidative phosphorylation pathway genes, IDH2 was the only gene that showed significantly (FDR < 0.05 with 1.5-fold cutoff) increased expression in both the SUDHL6 and SUDHL16 acquired venetoclax-resistant lines compared to their parental lines (Figure 4A).