MGMT and glioblastoma: Glioblastoma patients were categorized into 3 distinct genotypes based on the genetic and epigenetic characteristics of IDH1 and MGMT: GB patients with mutant IDH1/MGMT-met had the longest survival, followed by patients with mutant IDH1/MGMT-unmet or wildtype IDH1/MGMT-met, and patients with wildtype IDH1/MGMT-unmet had the shortest survival [52].