Overall, the immune cells investigated included B-cells, Natural killer (NK) cells, T-cells [Central memory (Tcm), Effector memory (Tem), Follicular helper (Tfh), CD4+ Helper (Th1 and Th2), CD8+, gamma delta (γδ), and regulatory T-cells (Tregs)], plasma cells, activated and inactivated dendritic cells (aDCs and iDCs, respectively), neutrophils, eosinophils, mast cells, M1 and M2 tumor-associated macrophages (TAMs), and myeloid-derived suppressor cells (MDSCs). Here, CD4 is linked to neoplasm.