CCR2 and multiple symmetric lipomatosis: In patients with the MSL subtype, featuring a high number of M2 TAMs, inhibition of the chemokine (C-C motif) ligand 2 (CCL2)/circulating chemokine-receptor-type 2 (CCR2) axis could decrease the recruitment of bone marrow mononuclear cells, subsequently reducing macrophage infiltration in the breast [58,59].