A detailed view into our DESeq2 Data revealed a clear shift to canonical BMP/TGFB-signaling in MSCs from myeloid neoplasms, especially for MDS and AML, reflected by a respective number of genes such as TGFB1, TGFB3L, and a low number of detected genes for MAPK-signaling (via JNK and ERK). The gene discussed is MAPK8; the disease is acute myeloid leukemia.