To investigate the roles of validated miRNA–gene pairs (miR-132-3p and miR-2110 targeting PIK3R3, miR-222-3p and miR-589-3p targeting STMN1) in cellular processes, such as cell proliferation and cell cycle progression, in different CRC cell models, miRNA mimics were transfected into a panel of CRC cell lines, then viability assayed using crystal violet assay. Here, STMN1 is linked to colorectal carcinoma.