Consistent with low WNT signaling in RevCSCs, BLM tumor stem cells had decreased expression of WNT/stemness-related genes compared to Min tumors such as Axin2, Id2, Sox4, Wnt6, Wnt10a, Id3, Prox1, and Id1 (Figure 5F, Supplemental Figure S5C). This evidence concerns the gene ID2 and neoplasm.