In patients affected by ischemic heart disease (IHD), Lisowska et al. found an average 1.25-fold increase in IGFBP7 serum levels in comparison to the population (1.76 ± 1 ng/mL vs. 1.43 ± 0.44 ng/mL, respectively, p = 0.019) [69]. The gene discussed is IGFBP7; the disease is myocardial ischemia.